A pair of NFC teams are set to meet in London this Sunday morning as we examine the latest Vikings vs Saints odds.

Minnesota (2-1) looked overmatched two weeks ago against a yet-undefeated Philadelphia Eagles squad but answered last week with a 28-24 victory over the Detroit Lions. The Saints, on the other hand, have dropped their last two games – including allowing Carolina their first win of the season last week – while starting quarterback Jameis Winston has been playing through a back injury of unknown severity.

Can Kevin O’Connell get the Vikings to a 3-1 start in his first year coaching the team, or will Dennis Allen get the Saints back up to 2-2 in his first year at the helm?

Vikings vs Saints Odds

Per BetMGM

  • Betting Favorite: Vikings -3
  • Moneyline Odds: Vikings -160, Saints +135
  • Point Total: 41.5 Over/Under
  • Location: Tottenham Hotspur Stadium, London, UK
  • Time/Network: 9:30 AM ET | NFL Network

The Vikings enter their third game as favorites this season after having won their past two, while the Saints enter their second game this season as an underdog after having lost in their first.

The teams are a combined 1-5 against the spread, with Minnesota only having covered in their opener against Green Bay. They’re also a combined 2-4 at hitting the over in their first three games, but only one of those games had a point total lower than the 41.5 these teams are looking at this week.

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Vikings vs Saints Injury Report

NFL betting is often impacted by the weekly injury reports Both teams enter Week 4 with an extensive list of injuries. How will it impact Vikings vs Saints odds?

Vikings

  • CB Andrew Booth (Quad)
  • RB Dalvin Cook (Shoulder)
  • FB C.J. Ham (Foot)
  • OLB Za’Darius Smith (Knee)
  • ILB Eric Kendricks (Toe)
  • FS Harrison Smith (Concussion)

Saints

  • CB Paulson Adebo (Ankle)
  • RB Alvin Kamara (Rib)
  • DE Marcus Davenport (Shoulder)
  • DB J.T. Gray (Shoulder)
  • WR Deonte Harty (Foot)
  • WR Tre’Quan Smith (Concussion)
  • TE Taysom Hill (Rib)
  • S Marcus Maye (Rib)
  • OT Ryan Ramczyk (Rest)
  • QB Jameis Winston (Back/Ankle)
  • WR Jarvis Landry (Ankle)
  • WR Michael Thomas (Foot)
  • G Andrus Peat (Concussion)

Andrew Booth’s name has been a consistent presence on the Vikings’ injury report this season, and Dalvin Cook – while a key player for the Vikings offense and fantasy football offenses everywhere – isn’t a stranger to the injury report either.

The absence of Eric Kendricks or Harrison Smith would be a major blow to the Vikings’ defense, but both players were full participants in practice on Wednesday and Thursday.

On the Saints end, none of the 13 players on their report were full participants in practice on Wednesday and three of them – Marcus Maye, Michael Thomas, and Andrus Peat – have already been ruled out for Sunday’s game.

While Ryan Ramczyk isn’t listed with an actual injury, few teams have graver health concerns than the Saints between the status of quarterback Jameis Winston (listed as doubtful for Sunday), offensive star Alvin Kamara (listed as questionable), and four wide receivers carrying injury designations.

Vikings vs Saints Head-to-Head

There are some memorable moments in Vikings vs Saints history. The teams last met at the end of the 2020 regular season – when the Saints won by a score of 52-33 in a game where Alvin Kamara tied the league record for single-game touchdowns (running, receiving, or returning) with six.

The teams have played four times dating back to the 2018 playoffs, where Stefon Diggs scored an iconic walk-off touchdown for the Vikings, splitting the series 2-2.

In looking at this year's Vikings vs Saints betting odds, this will be the first game in the series since that 2018 playoff match where the Vikings enter as the favorite, and the 41.5-point total is lower than any in the last ten Vikings vs Saints meetings.

Vikings recent record on the road

While this is not a true road game, Minnesota has struggled away from the friendly confines of US Bank Stadium.

  • The Vikings are 1-4 straight-up in their last five games on the road..
  • The Vikings are 1-4 ATS in their last five road games

Saints recent record at home

The game in Tottenspur Hotspur Stadium will be counted as a home game for the Saints. You'd think that would be a rough break, given the advantage New Orleans generally holds at the Superdome. However, they have struggled at home recently

  • The Saints are 1-4 in their last five home games
  • 1-4 against the spread in their last five homes

How will the neutral field impact Saints vs Vikings odds?

Vikings vs Saints Prediction

The away and home trends likely mean little for the Vikings vs Saints odds in London, but the injury reports and recent history clearly favor the Vikings.

The Saints could very well be starting backup quarterback Andy Dalton alongside a group of receivers that’ll be missing two or more of their top options. If the Vikings weren’t at some risk of being without defensive starters, they’d likely be favored to win by more.

The Saints might come out with a victory regardless, but it’ll involve showing us something from them that we have yet to see so far this season. The Vikings, even with the questions they have, are a far safer bet.

Prediction: Vikings 24, Saints 18

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