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Florida at Tennessee Predictions, Odds and Lines

Author: American Gambler Staff | Last Updated: September 23, 2022

Two SEC foes square off as we take a look at Florida vs Tennessee odds heading into a high-stakes clash down in Knoxville

Tennessee (3-0) will be looking to continue their undefeated start, while Florida (2-1) will be aiming to avoid an 0-2 start in Conference play. 

Both teams enter this contest ranked inside the top 25 with Tennessee  #11 and Florida #20. A signature win in Rocky Top would greatly boost each of these programs in the early stretch of the season.

Florida at tennessee predictions, odds and lines

Florida vs Tennessee Odds

  • Betting favorite: Tennessee (-10.5)
  • Moneyline odds: Florida (+290), Tennessee (-375)
  • Point total: 62.5
  • Location: Neyland Stadium, Knoxville, TN
  • Time/Network: 3:30 PM on CBS

After a dominating stretch of play to start the season, the Volunteers are getting plenty of respect here, opening up as a significant favorite over a tough Florida Gators team. 

Oddsmakers are anticipating a shootout with the over/under set at 62.5. There will be talented offensive playmakers all over the field in this one.

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Past weeks performances

It has been an up-and-down start for Florida, who have two tight wins over Utah and South Florida on their resume, along with a home loss to Kentucky. The Gators have struggled a bit on defense, allowing an average of nearly 27 points per game while yielding 195 rushing yards per contest.

Tennessee has come out of the gates on fire through their first three games, with their only test coming against Pittsburgh in Week 2, a game they won 34-27. Tennessee is putting up a whopping 52 points per game while averaging 553 yards.

Florida vs Tennessee Key Players

There are several playmakers on each side that have the capability to shift Florida vs Tennessee betting odds on Saturday. Here are some names to keep on your radar:


  • QB Anthony Richardson (Soph.)
  • RB Montrell Johnson (Soph.)
  • OG O’Cyrus Torrence (Sr.)
  • LB Brenton Cox (Sr.)
  • S Trey Dean (Sr.)


  • QB Hedon Hooker (Sr.)
  • WR Cedric Tillman (Sr.) 
  • OT Darnell Wright (Sr.)
  • LB Jeremy Banks (Sr.)
  • DE Byron Young (Sr.)

It will be worth monitoring the status of Cedric Tillman along with Vols running back Jabari Small, as both players are currently listed as questionable.

Tennessee vs Florida head-to-head

These teams are no strangers to one another playing in the SEC. 

Here’s a look at some betting trends from their recent matchups

  • Florida is 9-1 straight up in their last ten meetings
  • Florida is 3-1 ATS in their last four meetings
  • The under is 4-1 in their last five meetings

The Gators have owned a significant edge in this rivalry dating back for a decade. In recent years they have walloped the Vols with double-digit wins each of the last four seasons. 

Will Florida’s significant historical advantage play a role against this revamped Tennessee squad?

Florida recent road trends

After a 2-1 start at the Swamp, this will be the Gators' first road game of 2022. Here’s a look at how they fared a season ago:

Gators 2021 road trends

  • Straight up: 1-4
  • ATS: 0-5
  • ATS as an underdog: N/A

Tennessee recent record at Neyland Stadium

Tennessee comes in 2-0 both straight up and ATS as the home team so far in 2022. Their average margin of victory in those two contests was 57. Here’s a glance at how they performed at home last year:

Tennessee 2021 home trends

  • Straight up: 5-3
  • ATS: 3-5
  • ATS as the favorite: 3-2

Florida vs Tennessee predictions

Over the years, we’ve grown accustomed to seeing the Gators win this game and usually with ease. However, it looks like the tables have turned in 2022, with Tennessee (-10.5) opening as significant favorites. 

Florida’s defense has not played well to this point and looks particularly vulnerable against an explosive Vols unit that is averaging 553 yards per game.  Gators quarterback Anthony Richardson will need a massive performance to keep his team in this game. 

Florida has shown grit in pulling out two close home wins over the first three weeks, but they don’t have the talent to stack up with this Vols team. Look for the Tennessee offense to exploit mismatches and have no issues moving the ball on the ground and through the air. 

Prediction: Tennessee 41, Florida 27

More Florida vs Tennessee picks to consider:

  • Over 62.5 (-110)
  • Tennessee 1H spread (-6)
  • Tennessee to win and over 60.5 points scored (+110)
Florida at tennessee predictions, odds and lines


American Gambler Staff