Two ranked ACC Atlantic teams are set to play this Saturday in Memorial Stadium as we examine the latest Clemson vs NC State odds.

Both teams are 4-0 entering the weekend and – for the first time in series history – ranked in the AP Top 10. Clemson enters the week as a slight favorite, but they barely escaped last week with a win after going to double overtime against Wake Forest.

Can the Wolfpack open their conference schedule with an upset and challenge the balance of power in the ACC?

NC State vs Clemson Odds

Per BetMGM

  • Betting Favorite: Clemson -6.5
  • Moneyline Odds: Clemson -250, NC State +200
  • Point Total: 42 Over/Under
  • Location: Memorial Stadium, Clemson, SC
  • Time/Network: 7:30 PM EST | ABC

In looking at these NC State vs Clemson odds, the Tigers enter as modest home favorites. Despite the fact that both offenses exploded for 40+ points a week ago, oddsmakers are expecting more of a defensive battle here, with the over/under set at just 40.5.

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Last Week’s Performances

Clemson comes into the week after a 51-45 double overtime victory in Winston-Salem over another ranked ACC Atlantic rival in Wake Forest. While it was the closest game of Clemson’s young 2022 football season, it was enough to lift them to a 2-0 conference record alongside their 41-10 opening week disassembly of Georgia Tech.

NC State had a 41-10 victory of their own last week against the UConn Huskies, but have yet to play a conference game this season.

NC State vs Clemson Key Players

Here's a look at some top players on each side with the capability to shift NC State vs Clemson betting odds

Clemson

  • QB D.J. Uiagalelei
  • WR Beaux Collins
  • DE Myles Murphy
  • DT Bryan Breesee

NC State

  • QB Devin Leary
  • RB Demie Sumo-Karngbaye
  • WR Thayer Thomas
  • LB Drake Thomas

Clemson vs NC State Head-to-Head

  • Clemson is 8-2 in their last 10 meetings
  • NC State is 6-4 against the spread in those 10 meetings.
  • The point total went over in 5 of those 10 meetings (9 of them had point totals set above 50.)

The Wolfpack narrowly escaped Greenville with a victory against East Carolina in their only road game thus far of the 2022 football season. Their last three road games to end the 2021 season include a 28-14 victory over Florida State and losses to Wake Forest and Miami by a combined total of 4 points. They went a total of 1-3 against the spread over that stretch.

2021 NC State road trends

  • Straight up: 2-3
  • ATS: 2-3
  • ATS as an underdog: 0-1

Clemson Recent Record at Memorial Stadium

Clemson has come out victorious in each of their last ten games, including five at home and two earlier in the 2022 season against Furman and Louisiana Tech. While the spreads in those games favored Clemson by a wide margin (-45.5 against Furman and -33.5 against Louisiana Tech), they went 0-2 against the spread through both games.

2021 Clemson home trends

  • Straight up: 6-0
  • ATS: 2-4
  • ATS as a favorite: 2-4

Clemson vs NC State Prediction

In looking at the latest Clemson vs NC state odds, it’s curious that Clemson is looking at a point total of 42 to beat when they’ve scored enough points in 3 of their first 4 contests to hit that over on their own.

NC State hasn’t struggled to move the ball either – at least in more recent games. It wouldn’t be shocking if the point total was in the rearview mirror by the third quarter.

Beyond that, Clemson has a better defensive line with names like Myles Murphy, Bryan Bresee, and K.J. Henry. The trio has recorded a modest three sacks between them through the first four games, but they might have a chance to create pressure and become the stars of the show if this game becomes a shootout.

Look for plenty of offense and a game that comes right down to the wire.

Prediction: Clemson 37, NC State 33

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