What to Know: The 49ers closed the 2017 season strong and a lot was expected in 2018. Then quarterback Jimmy Garoppolo was lost for the season and it all fell apart. With a healthy quarterback the team should rebound nicely in 2018. As always they were busy in free agency and added some good players on defense in linebackers Dee Ford and Kwon Alexander and cornerback Jason Verret.
Best Players: Garoppolo, when he is healthy, is a good quarterback. Free agent running back Tevin Coleman, from Atlanta, will be a good addition to the running game.
How to Bet: This is another team that, at times, gets overbet or overrated. Stay away from them as a favorite, but if you can get them with points, especially at home, it could be profitable.