Detroit Lions vs San Francisco 49ers – Picks & Predictions

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Detroit Lions vs San Francisco 49ers – Picks & Predictions

Author: Andy Hammel | Publish Date: January 26, 2024 | Last Updated: January 26, 2024

The NFC Championship game kicks off this Sunday between the regular season champion San Francisco 49ers (13-5) and visiting Detroit Lions (14-5). Betting markets will be available at across US betting apps, including moneylines, spreads, totals, player and team props, and several same-game parlay options. New customers can also claim NFL betting promos all postseason long.

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Head-to-Head: Detroit Lions vs San Francisco 49ers

Both of these teams finished the regular season with 12-5 records, with the 49ers having the tiebreaker advantage due to their better record against NFC opponents. Both teams suffered three one-score losses and bad losses against the Baltimore Ravens – who still loom as a potential Super Bowl opponent for whoever wins Sunday – but fielded offenses that carried the day against far more of their opponents than not. The 49ers led the league in offensive DVOA and ranked second in total DVOA; the Lions ranked fifth and seventh.

The Lions’ last road game ended in a controversial 19-20 loss to the Cowboys, but they’ve gone 3-0 at home against the Vikings, Rams, and Buccaneers to make it to the NFC Championship. Jared Goff has completed 52 of 70 passes for 564 yards and three touchdowns through the playoffs thus far. Amon-Ra St. Brown was targeted on 21 of those passes, and converted them into 187 yards and a touchdown on 15 catches.

The 49ers’ offense has ebbed and flowed with the health of their key contributors, most notably do-it-all offensive weapon Deebo Samuel. A shoulder injury sidelined Samuel during the 49ers’ meeting with the Browns in Week 7, marking the beginning of an 0-3 stretch that ended when Samuel returned to the lineup against the Jagaurs in Week 10. After leaving the 49ers’ divisional round win against the Packers with another shoulder injury, Samuel’s status for the NFC Championship remains in question.

How to Bet on Detroit Lions vs San Francisco 49ers

Betting markets for the NFC Championship game will be available at online sportsbooks across America. Make sure to browse your available options to find the best odds for the bets you want to make, as well as any props or promotions only offered at particular sportsbooks.

Additionally, be sure to check the injury report and weather outlook for the game ahead of placing any bets. Player health and playing conditions are significant variables in the outcome of NFL games, especially when marquee players are on the line.

Detroit Lions vs San Francisco 49ers Odds

  • Money Line: Detroit Lions +280 San Francisco 49ers -350
  • Spread: SF -7.0
  • Total: o/u 50.5

Betting Tips for Detroit Lions vs San Francisco 49ers

  • The 49ers are 1-3 ATS in their last four games.
  • The Lions are 5-1 ATS in their last six games.
  • The 49ers have scored first in 8 of their last 10 home games.
  • The 49ers have hit the 4Q Game Total Under in their last 5 home games.
  • The Lions have hit the 3Q Game Total Over in 10 of their last 11 games.

Detroit Lions vs San Francisco 49ers Predictions

Expect the lines to move significantly if Deebo Samuel is ultimately ruled out of this game, but early indications are that he’ll suit up. Both teams enter this matchup with outstanding bodies of work on offense, but the 49ers’ defense has done notably better this season in DVOA (4th), and ranks eight in yards (305.4) and third in points (17.4) allowed per game. The 49ers’ defense held 11 of their opponents this season to fewer than 20 points, something the Lions’ only accomplished 4 times. That unit could win the 49ers the game come Sunday.

Prediction: San Francisco 49ers -7

Andy Hammel

Andy is our resident NFL expert, but his knowledge extends to all corners of the sports betting industry. Andy is always tracking betting trends and keeping you up to date on all the relevant news in your home state.